Persistent organic pollutants as risk factors for type 2 diabetes

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Persistent organic pollutants as risk factors for type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a major and fast growing public health problem. Although obesity is considered to be the main driver of the pandemic of T2DM, a possible contribution of some environmental contaminants, of which persistent organic pollutants (POPs) form a particular class, has been suggested. POPs are organic compounds that are resistant to environmental degradation through ch...

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Association Between Type 2 Diabetes and Exposure to Persistent Organic Pollutants

OBJECTIVE The prevalence of type 2 diabetes is increasing alarmingly in both developed and developing countries. Recently, exposure to persistent organic pollutants (POPs) has been associated with the prevalence of type 2 diabetes. The purpose of this cross-sectional study is to examine the association between type 2 diabetes and POP exposure in the Helsinki Birth Cohort Study. RESEARCH DESIG...

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Low Dose of Some Persistent Organic Pollutants Predicts Type 2 Diabetes: A Nested Case–Control Study

BACKGROUND Low doses of some persistent organic pollutants (POPs) associate cross-sectionally with type 2 diabetes, whereas associations with high POP exposures are inconsistent. OBJECTIVES We investigated whether several POPs prospectively predict type 2 diabetes within the Coronary Artery Risk Development in Young Adults (CARDIA) cohort. METHODS Participants in this nested case-control st...

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Persistent Organic Pollutants and Obesity-Related Metabolic Dysfunction: Focusing on Type 2 Diabetes

Even though obesity is a well-established risk factor of type 2 diabetes, there is emerging evidence that persistent organic pollutants (POPs), a variety of lipophilic chemicals accumulated in adipose tissue, may be critically involved in the pathogenesis of type 2 diabetes. Among various POPs, serum concentrations of organochlorine pesticides and polychlorinated biphenyls (PCBs) were the most ...

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Persistent organic pollutants (POPs) as environmental risk factors in remote high-altitude ecosystems.

Persistent organic pollutants (POPs), and their transformation products, are the most investigated organic environmental contaminants within the past five decades. Organochlorines have been found in virtually all environmental compartments on the globe. Severe environmental implications have been shown to be associated with the presence of the POP group of contaminants in the environment. Howev...

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ژورنال

عنوان ژورنال: Diabetology & Metabolic Syndrome

سال: 2015

ISSN: 1758-5996

DOI: 10.1186/s13098-015-0031-6